猪圆环病毒2型合并感染脑心肌炎病毒对仔猪的致病性分析

doi:10.11843/j.issn.0366-6964.2016.07.017

Abstract

Abstract:

The objective of our research was to evaluate the growth performance and pathogenicity of piglets concurrent infection with porcine encepholomyocarditis virus (EMCV) under immunosuppression condition caused by porcine circovirus type 2 (PCV-2).Sixteen piglets were chosen for three challenge groups including EMCV，PCV-2 and concurrent infection with PCV-2 and EMCV，and control group.The effect of concurrent infection on piglets was conducted by the relevant indexes including clinical symptoms，pathological examinations，growth performances，immune index，detoxification and so on.The results indicated that the groups infection only with EMCV or PCV-2 showed their own classical clinical characteristic and minimal injury.However，the mortality rate of concurrent infection increased rapidly，the average daily weight gain decreased significantly，degeneration and necrosis in myocardium and brain tissues was more severe，the lymphocyte ratio in the blood still remained low and the neutraliz-ation antibody of EMCV maintained at a low level in a long time.The piglets shed virus lasted 12 days after infection，longer than the group infected only with EMCV for 9 days.The results showed that PCV-2 early infection can promote more severe pathogenicity and lethality，and lower immunity in piglets induced by EMCV，and the ability of virus replication and detoxification in piglets enhanced.

CLC Number:

S858.285.3

CHANG Hong-tao，LIU Hui-min，LI Yong-tao，HE Xiu-yuan，ZHAO Jun，CHEN Lu，WANG Xin-wei，YANG Xia，WANG Chuan-qing. Analysis of Pathogenicity in Piglets Concurrent Infection with Encepholomyocarditis Virus under Immunosuppression Caused by Porcine Circovirus Type 2[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2016, 47(7): 1435-1442.

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Analysis of Pathogenicity in Piglets Concurrent Infection with Encepholomyocarditis Virus under Immunosuppression Caused by Porcine Circovirus Type 2

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